Omega-3 fatty acids are well-known
for a bounty of health benefits ranging from cardiovascular health to healthy
joints, but according to a study conducted by researchers from Ohio State
University, omega-3s may also help to protect your DNA from the effects of
natural aging.
The study, published in the Brain, Behavior,
and Immunity Peer Review Journal, found that regular omega
supplementation for a period of 4+ months could help to slow the biological
effects of aging. In the trial, participants took either 2.5 grams or 1.25
grams of active Omega-3 polyunsaturated fatty acids compared against a third
group given a placebo. Each omega-3 supplement contained a 7:1 ratio of
eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA).
How do cells biologically age?
Omega-3 fatty acids are well-known for
a bounty of health benefits ranging from cardiovascular health to healthy
joints, but according to a study conducted by researchers from Ohio State
University, omega-3s may also help to protect your DNA from the effects of
natural aging.
The study, published in the Brain, Behavior,
and Immunity Peer Review Journal, found that regular omega
supplementation for a period of 4+ months could help to slow the biological
effects of aging. In the trial, participants took either 2.5 grams or 1.25
grams of active Omega-3 polyunsaturated fatty acids compared against a third
group given a placebo. Each omega-3 supplement contained a 7:1 ratio of
eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA).
What the study found:
Professor Kiecolt-Glaser led the
study, and confirmed regular supplementation with omega-3 reduced oxidative
stress by as much as 15% when compared to the placebo group. The researchers
found omega supplementation transformed the natural ratio of omega-6: omega-3
fatty acids and preserved the length of the telomeres in each participant’s
DNA. As that ratio became lower, the average length of each participant’s
DNA-protective telomeres became significantly longer.
Why does this work?
Human beings naturally produce
arachidonic acid (AA), an omega-6 fatty acid which promotes cellular
inflammation. EPA inhibits the production and release of AA, lowering the amount
of harmful omega-6 fatty acids in the body. Most people simply don’t get enough
omega-3 fatty acids in their diet to achieve a low omega-6:omega-3 ratio,
leaving the body and DNA especially vulnerable to oxidative damage.
“The telomere finding is provocative in that it suggests
the possibility that a nutritional supplement might actually make a difference”
says Ohio State’s Dr. Jan Kiecolt-Glaser.
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