Tuesday, November 12, 2013

Critically Ill Have Reduced Levels of CoQ10


An article published in the Journal of Critical Care revealed lower levels of coenzyme Q10 (CoQ10) in critically ill patients in comparison with healthy men and women.*
The study compared 36 adult intensive care unit patients with 18 healthy controls. Septic shock was present in 12 of the critically ill subjects. While the lowest levels of plasma CoQ10 occurred in septic shock patients, levels were lower in critically ill patients both with and without septic shock in comparison with healthy subjects. Reduced levels of CoQ10 were also associated with increased age and with a decline in the ability to perform activities of daily living after hospital discharge. Authors Andrea Coppadoro and colleagues remark that CoQ10 supplementation has been associated with improvement in activities of daily living scores, neuromuscular function, and other long-term outcomes in certain groups, suggesting that supplementation could also benefit the outcome of the critically ill.
—D. Dye
Reference
* J Crit Care. 2013 Apr 22.

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