Tuesday, November 19, 2013

Wednesday, November 13, 2013

Did you know a vitamin D deficiency more than DOUBLES your risk of type II diabetes?


Just a few years ago, vitamin D was simply known as the “bone vitamin.” Thanks to the hard work of many scientists, especially Michael Holick, MD, a pioneer in vitamin D research, the data show that nearly every tissue and cell type in the body has receptors for vitamin D. As a result of this discovery, much higher doses are required for optimal functioning. This discovery has radically changed how we understand the role of vitamin D in the body.
            Unless you body is at optimal levels, you are opening the door to a host of disorders, ranging from heart disease and Alzheimer’s to weak bodes and diabetes.
            In fact, even if you have normal blood sugar today, a vitamin D deficiency makes you 91% more likely to progress to insulin resistance, or “pre-diabetes,” and it more than doubles your risk from progressing to active, type II diabetes.
            Unfortunately, vitamin D deficiency is a global epidemic. An estimated 1 billion people do not have adequate vitamin D levels. And 64% of Americans don’t have enough vitamin D to keep all of their tissues operating at peak capacity.
            The results of this deficiency are catastrophic. Studies have now shown that vitamin D deficiency is associated with increased risk of a long list of diseases that span all systems of the body. In fact, low levels of vitamin D increase the risk of non-Alzheimer’s dementia almost 20 times!
            While checking for vitamin D levels is still not standard care for many physicians, you will realize from reading this article that assessing vitamin D status is one of the most important health protecting steps you can take. Fortunately, achieving optimal levels of vitamin D is easy, inexpensive, and highly protective against a range of lethal diseases. 






Tuesday, November 12, 2013

Critically Ill Have Reduced Levels of CoQ10


An article published in the Journal of Critical Care revealed lower levels of coenzyme Q10 (CoQ10) in critically ill patients in comparison with healthy men and women.*
The study compared 36 adult intensive care unit patients with 18 healthy controls. Septic shock was present in 12 of the critically ill subjects. While the lowest levels of plasma CoQ10 occurred in septic shock patients, levels were lower in critically ill patients both with and without septic shock in comparison with healthy subjects. Reduced levels of CoQ10 were also associated with increased age and with a decline in the ability to perform activities of daily living after hospital discharge. Authors Andrea Coppadoro and colleagues remark that CoQ10 supplementation has been associated with improvement in activities of daily living scores, neuromuscular function, and other long-term outcomes in certain groups, suggesting that supplementation could also benefit the outcome of the critically ill.
—D. Dye
Reference
* J Crit Care. 2013 Apr 22.

High Homocysteine, Low Folate, and B12 Predict Macular Degeneration


An article published in the American Journal of Clinical Nutrition reports the finding of a protective effect for higher levels of vitamin B12 and folate against the risk of developing age-related macular degeneration (AMD).* The study also revealed a greater risk of AMD in association with higher levels of homocysteine.
Paul Mitchell and his colleagues analyzed data from 1,390 participants in the Blue Mountains Eye Study of common eye diseases. Eye examinations were conducted upon enrollment and at five, ten, and fifteen years. Serum homocysteine, folate, and vitamin B12 levels were measured and dietary questionnaires were completed at the five-year follow-up visit.
From the five-year through the fifteen-year follow-up visit, 219 subjects were diagnosed with AMD. In comparison with those with lower homocysteine levels, participants whose levels were greater than 15 micromoles per liter had an up to 56% greater risk of AMD.
Editor’s Note: Among those with deficient folate levels, the risk of AMD was up to 89% higher in comparison with the risk experienced by subjects with greater levels. Vitamin B12 deficiency also increased risk.
—D. Dye
Reference Am J Clin Nutr. 2013 May 1.


Monday, November 11, 2013

In Related News: Vitamin D May Protect Against the Development of Uterine Fibroids

A recent issue of Epidemiology published an article that reports the finding of vitamin D researcher Bruce W. Hollis and his colleagues of a lower risk of uterine fibroid tumors in women with sufficient levels of vitamin D.*
The study evaluated 620 African American women and 416 Caucasian women between the ages of 35 to 49 who were enrolled in the National Institute of Environmental Health Sciences Uterine Fibroid Study. Serum 25-hydroxyvitamin D levels were measured in blood samples collected upon enrollment, and ultrasound examinations ascertained the presence and size of fibroids.
Subjects with sufficient serum levels of the vitamin, which the researchers classified as 20 ng/mL or higher, had a 32% lower risk of having fibroids in comparison with those whose levels were sufficient. Each 10 ng/mL increase in vitamin D was associated with a 20% reduction in fibroid risk.
—D. Dye
Reference
* Epidemiology. 2013 May;24(3):447-53.

Thursday, November 7, 2013

Study Results Indicate Benefits of Antioxidants Following Breast Cancer Therapy



In honor of breast cancer awareness month, for anyone you know who has breast cancer, the risk of breast cancer recurrence was 36% lower in association with the use of Vitamin D. 

An article published in Breast Cancer Research and Treatment reports that supplementation with antioxidants after treatment for breast cancer is not only safe, but may help improve survival.*
Elizabeth M. Poole of Harvard University and her associates analyzed data from 12,019 breast cancer survivors enrolled in one of four studies included in the After Breast Cancer Pooling Project. The analysis examined the use of supplements at least one year after diagnosis. Over follow-up, 1,298 deaths occurred, of which 65% were due to breast cancer.
Sixty percent of the women reported using supplements from one-to-five years following diagnosis. The use of any antioxidant supplement, categorized as vitamins C, E, or a multivitamin supplement in this study, was associated with a 16% lower adjusted risk of dying from any cause over follow-up, and for those who used all three supplements, the risk was 21% lower.
The risk of breast cancer recurrence was 36% lower in association with the use of vitamin D among women with estrogen receptor-positive tumors.
—D. Dye
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Reference: *Breast Cancer Res Treat, 2013 May 10